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Table 3 BMI independently predicts structural brain volume in older adults with heart failure ( N= 80)

From: Higher BMI is associated with reduced brain volume in heart failure

  WMH TBV Total GM Subcortical GM WM
β SE b β SE b β SE b β SE b β SE b
Block 1  
Age, years .23* .02 -.11 1346.84 -.08 811.00 -.14 299.99 -.12 1799.30
Sex -.15 .41 .01 32167.72 -.22 19369.89 -.12 7164.93 .12 42974.36
Education, years -.29* .05 .09 4304.00 -.01 2591.67 .16 958.66 .10 5749.92
LVEF % -.15 .01 -.03 864.47 .03 520.54 -.03 192.55 -.04 1154.89
Hypertension -.01 .34 .13 26933.65 -.18 16218.18 .04 5999.12 .20 35981.92
Diabetes .08 .34 -.07 26560.24 -.11 15993.33 -.16 5915.94 -.05 35483.06
Sleep apnea -.13 .37 .03 29212.06 .09 17590.13 .15 6506.60 .02 39025.75
MI .11 .30 .05 23499.98 -.14 14150.58 -.16 5234.31 .08 31394.71
Depression -.03 .39 .04 31194.14 -.07 18783.64 .01 6948.08 .06 41673.70
ICV .23 .00 .81** .08 .63 .05 .58** .02 .53** .11
R 2 .25 .67 .38 .35 .40
F 2.25* 14.16* 4.19* 3.68** 4.65**
Block 2  
CBF-V, cm/s -.25* .01 .08 918.63 .04 556.68 .09 205.01 .09 1229.93
R 2 .30 .68 .38 .36 .41
F for ΔR2 6.67* .98 .11 .71 .68
Block 3  
BMI, kg/m2 .12 .03 -.16 2166.43 .19 1323.46 -.22 484.27 -.26* 2876.44
R 2 .30 .69 .40 .38 .45
F for ΔR2 .78 3.35 2.22 3.12 4.53*
  1. Note. *p ≤ 0.05; **p < .01; sex: 1 = males and 0 = females; 1 = positive history and 0 = negative history for hypertension, diabetes, sleep apnea, MI, and depression.
  2. Abbreviations: β – standardized regression coefficients, SE standard error; BMI Body Mass Index; MI Myocardial infarction; ICV Intracranial Volume; CBF-V Cerebral Blood Velocity of the MCA; WMH White Matter Hyperintensities; GM Gray Matter; WM White Matter Volume.
  3. Volumetric indices units = mm3.