Prevention | Reversal | ||||||
---|---|---|---|---|---|---|---|
HFD | HFD | HFD | Normal | HFD | HFD | HFD | |
CO-28 | CO-200 | Control | Control | CO-28 | CO-200 | Control | |
(n = 4) | (n = 4) | (n = 4) | (n = 4) | (n = 4) | (n = 4) | (n = 4) | |
VO2 (ml/kg/min) | 54.2 ± 8.2 | 50.3 ± 8.1 | 55.6 ± 2.8 | 61.5 ± 5.7 | 56.5 ± 12.4 | 55.8 ± 8.8 | 52.7 ± 8.7 |
VCO2 (ml/kg/min) | 40.3 ± 6.5 | 37.0 ± 7.3 | 40.7 ± 2.4 | 46.0 ± 4.4 | 41.2 ± 9.6 | 40.7 ± 6.5 | 39.1 ± 7.5 |
RER | 0.73 ± 0.02 | 0.73 ± 0.04 | 0.73 ± 0.02 | 0.74 ± 0.02 | 0.73 ± 0.03 | 0.73 ± 0.01 | 0.74 ± 0.02 |
Heat Prod. (Cal/hr) | 826 ± 135 | 797 ± 105 | 857 ± 43 | 605 ± 68* | 828 ± 168 | 912 ± 158 | 883 ± 84 |
Motor Act. (m/day) | 3.88 ± 0.90 | 3.39 ± 0.56 | 4.44 ± 1.84 | 8.87 ± 1.51* | 4.52 ± 2.15 | 6.76 ± 3.24 | 3.77 ± 2.94 |
Food 10 weeks (g/day) | 2.8 ± 0.1 | 2.5 ± 0.2 | 2.2 ± 0.1# | 3.2 ± 0.8 | 3.7 ± 0.4 | 3.0 ± 0.1 | 3.2 ± 0.4 |
Food 28 weeks (g/day) | 3.0 ± 0.2 | 3.0 ± 0.4 | 3.3 ± 0.8 | 3.4 ± 0.3 | 3.2 ± 0.2 | 3.4 ± 0.3 | 3.2 ± 0.3 |