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Table 2 Delta changes in baseline parameters after 52 weeks according to randomization group

From: Cardiac natriuretic peptides in plasma increase after dietary induced weight loss in obesity

  Intervention (n = 28) Control (n =24) Mean difference (95% CI) P value (differences between groups)
∆ Weight (kg) −14.2 ± 1.6a −6.1 ± 1.2a −8.8 (−12.3, −3.9) <0.0001
∆ BMI (kg/m2) −5.4 ± 0.6a −2.2 ± 0.3a −3.2 (−4.8, −1.6) <0.0001
∆ Fat mass (kg) −11.5 ± 1.5a −4.4 ± 1.2a −7.0 (−11, −3.1) 0.001
∆ Fat-free mass (kg) −0.9 ± 0.5c −0.5 ± 4.0c −0.4 (−1.7, 0.9) 0.54
∆ NT-proBNP (pg/ml) 42 ± 9a 4 ± 7c −38 (−61, −14) 0.002
∆ MR-proANP (pmol/l) 15 ± 4b 5 ± 5c −11 (−22, 1) 0.071
∆ MR-proADM (pmol/l) −56 ± 15b −19 ± 35b 37 (−37, 111) 0.32
∆ Plasma glucose (mmol/l) −0.6 ± 0.3a −0.4 ± 0.3a −0.2 (−0.4, 0.2) 0.31
∆ CRP (mg/l) −2.0 ± 0.9b −0.9 ± 1.3c −1.2 (−4.3, 2.0) 0.46
∆ Cholesterol (mmol/l) −0.2 ± 0.2c 0.03 ± 0.2c −0.3 (−0.6, 0.3) 0.50
∆ LDL cholesterol (mmol/l) −0.2 ± 0.1c −0.2 ± 0.1c 0.1 (−0.3, 0.5) 0.70
∆ HDL cholesterol (mmol/l) 0.1 ± 0.1b 0.2 ± 0.1b 0.1 (−0.1, 0.3) 0.22
∆ Triglycerides (mmol/l) −0.5 ± 0.2b 0.05 ± 0.1c −0.5 (−1.1, 0.1) 0.083
∆ s-creatinine (μmol/l) −3.0 ± 1.0b −5.0 ± 2.0b 1.8 (−3, 7) 0.45
∆ eGFR (ml/min) 6.1 ± 3.0d 7.0 ± 3.0b 1.0 (−8, 10) 0.82
  1. Data are expressed as mean ± SEM, if not stated otherwise. NS, Not significant.
  2. aP < 0.001, compared to baseline.
  3. bP < 0.05, compared to baseline.
  4. cno significant difference from baseline.
  5. dP = 0.051.