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Figure 3 | BMC Obesity

Figure 3

From: Polybrominated diphenyl ether congener, BDE-47, impairs insulin sensitivity in mice with liver-specific Pten deficiency

Figure 3

BDE-47 does not significantly impact plasma insulin concentrations or hepatic triglyceride content. A) Mean plasma insulin (ng/ml) determined at 30 minutes following glucose administration during GTT tests. B) Mean hepatic triglyceride levels (mg/g) following 6 weeks of BDE-47 or DMSO treatment. *, p < 0.05 compared to DMSO-treated control and Tsc1−/− mice. C) H&E histology of liver showing examples from each of the treated groups. Original magnification 400x. D) Expression of indicated genes in liver tissues based on qRT-PCR analyses. #, p < 0.05 compared to DMSO-treated control; *, p < 0.05 compared to DMSO-treated Tsc1−/− mice; **, p < 0.05 compared to DMSO-treated control and Pten−/− mice.

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BMC Obesity

ISSN: 2052-9538

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