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Table 1 Study participant characteristics and their linear associations with leukocyte telomere lengtha
| Sample characteristic | Leukocyte telomere length tertile† | Pearson’s correlation coefficient¶ | Linear regression | |||||
|---|---|---|---|---|---|---|---|---|
| n | Short (n = 96) | Middle (n = 99) | Long (n = 100) | Age & gender adjusted beta (95 % CI) | P-value | |||
| Leukocyte telomere length (T/S ratio)† | 295 | 0.68 (0.05) | 0.78 (0.03) | 0.90 (0.08) | - | - | - | |
| Age (per year) † | 295 | 65.5 (10.9) | 62.0 (12.0) | 57.0 (10.8) | −0.30₤ | −0.003 (−0.004,-0.002)₤ | <0.001 | |
| Gender ‡ | Male | 236 | 84 (87.5) | 78 (78.8) | 74 (74.0) | - | REF | - |
| Female | 59 | 12 (12.5) | 21 (21.2) | 26 (26.0) | - | 0.04 (0.01,0.07)€ | 0.01 | |
| BMI (per kg/m2) † | 290 | 28.1 (3.6) | 29.2 (4.5) | 29.1 (4.3) | 0.05 | 0.002 (−0.002,0.005) | 0.35 | |
| Waist-hip ratio (per unit) † | 294 | 0.95 (0.06) | 0.96 (0.07) | 0.95 (0.07) | 0.05 | 0.10 (−0.13, 0.34) | 0.38 | |
| Waist circumference (per inch) † | 294 | 39.2 (4.0) | 39.6 (4.9) | 39.6 (4.4) | 0.09 | 0.002 (−0.001, 0.005) | 0.14 | |
| Cigarette use ‡ | Never | 100 | 33 (34.4) | 29 (29.3) | 38 (38.0) | - | REF | - |
| Ever | 195 | 63 (65.6) | 70 (70.7) | 62 (62.0) | - | −0.007 (−0.03, 0.02) | 0.64 | |
| Cigarette pack-years (per pack-year) † | 195 | 34.0 (25.6) | 23.6 (24.8) | 18.5 (19.1) | −0.11 | −0.0006 (−0.0011,−0.0000) | 0.04 | |
| Alcoholic drinks/day (per drink) † | 240 | 1.7 (4.9) | 1.4 (7.9) | 1.0 (2.5) | −0.07 | −0.002 (−0.004, 0.001) | 0.20 | |
| NSAID use ‡ | Non-current | 190 | 58 (60.4) | 64 (64.7) | 68 (68.0) | - | REF | - |
| Current | 105 | 38 (39.6) | 35 (35.3) | 32 (32.0) | - | −0.001 (−0.029, 0.027) | 0.93 | |
| Statin use ‡ | Non-current | 265 | 83 (86.5) | 92 (92.9) | 90 (90.0) | - | REF | |
| Current | 30 | 13 (13.5) | 7 (7.1) | 10 (10.0) | - | −0.023 (−0.066, 0.020) | 0.29 | |
