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Table 1 Study participant characteristics and their linear associations with leukocyte telomere lengtha

From: Obesity and inflammation markers in relation to leukocyte telomere length in a cross-sectional study of persons with Barrett’s esophagus

Sample characteristic

 

Leukocyte telomere length tertile†

Pearson’s correlation coefficient

Linear regression

n

Short (n = 96)

Middle (n = 99)

Long (n = 100)

Age & gender adjusted beta (95 % CI)

P-value

Leukocyte telomere length (T/S ratio)†

 

295

0.68 (0.05)

0.78 (0.03)

0.90 (0.08)

-

-

-

Age (per year) †

 

295

65.5 (10.9)

62.0 (12.0)

57.0 (10.8)

−0.30

−0.003 (−0.004,-0.002)

<0.001

Gender ‡

Male

236

84 (87.5)

78 (78.8)

74 (74.0)

-

REF

-

 

Female

59

12 (12.5)

21 (21.2)

26 (26.0)

-

0.04 (0.01,0.07)

0.01

BMI (per kg/m2) †

 

290

28.1 (3.6)

29.2 (4.5)

29.1 (4.3)

0.05

0.002 (−0.002,0.005)

0.35

Waist-hip ratio (per unit) †

 

294

0.95 (0.06)

0.96 (0.07)

0.95 (0.07)

0.05

0.10 (−0.13, 0.34)

0.38

Waist circumference (per inch) †

 

294

39.2 (4.0)

39.6 (4.9)

39.6 (4.4)

0.09

0.002 (−0.001, 0.005)

0.14

Cigarette use ‡

Never

100

33 (34.4)

29 (29.3)

38 (38.0)

-

REF

-

 

Ever

195

63 (65.6)

70 (70.7)

62 (62.0)

-

−0.007 (−0.03, 0.02)

0.64

Cigarette pack-years (per pack-year) †

 

195

34.0 (25.6)

23.6 (24.8)

18.5 (19.1)

−0.11

−0.0006 (−0.0011,−0.0000)

0.04

Alcoholic drinks/day (per drink) †

 

240

1.7 (4.9)

1.4 (7.9)

1.0 (2.5)

−0.07

−0.002 (−0.004, 0.001)

0.20

NSAID use ‡

Non-current

190

58 (60.4)

64 (64.7)

68 (68.0)

-

REF

-

 

Current

105

38 (39.6)

35 (35.3)

32 (32.0)

-

−0.001 (−0.029, 0.027)

0.93

Statin use ‡

Non-current

265

83 (86.5)

92 (92.9)

90 (90.0)

-

REF

 
 

Current

30

13 (13.5)

7 (7.1)

10 (10.0)

-

−0.023 (−0.066, 0.020)

0.29

  1. Leukocyte telomere length tertile: Short < 0.735, Middle 0.735-0.846, Long ≥ 0.847
  2. † = Median (Standard deviation), ‡ = Frequency (%), ₤ = Adjusted only for gender, ¶ = Adjusted for age & gender
  3. BMI body mass index, NSAID non-steroidal anti-inflammatory drugs, CI confidence interval
  4. aThe correlation and regression values are based on leukocyte telomere length as a continuous variable