|
Group A - control
|
Group B - formoline L112
|
---|
Animal number
|
A1
|
A2
|
A3
|
A4
|
A5
|
Mean ± SD
|
B1
|
B2
|
B3
|
B4
|
B5
|
B6
|
Mean ± SD
|
---|
Body weight (kg):
|
At acclimatisation
|
25.6
|
30.1
|
34.5
|
31.7
|
28.3
|
30.0 ± 3.4
|
32.2
|
30.0
|
31.4
|
30.5
|
33.9
|
31.4
|
31.6 ± 1.4
|
At dosing
|
26.0
|
27.7
|
31.9
|
31.3
|
27.6
|
28.9 ± 2.6
|
32.2
|
31.4
|
28.8
|
30.5
|
31.6
|
31.2
|
31.0 ± 1.2
|
At sacrifice
|
25.8
|
27.2
|
31.8
|
30.0
|
27.4
|
28.4 ± 2.4
|
32.9
|
29.6
|
28.2
|
28.2
|
30.4
|
30.0
|
29.9 ± 1.7
|
Dose (mg/kg)
|
9.78
|
9.89
|
9.92
|
9.92
|
9.89
|
9.88 ± 0.06
|
10.0
|
9.88
|
9.91
|
9.91
|
9.92
|
9.93
|
9.93 ± 0.04
|
Radioactivity (MBq/kg)
|
0.42
|
0.43
|
0.43
|
0.43
|
0.43
|
0.43 ± 0.00
|
0.43
|
0.43
|
0.43
|
0.43
|
0.43
|
0.43
|
0.43 ± 0.00
|
- Values are presented as individual and mean ± standard deviation