TY - JOUR AU - Mato, Edith Pascale M. AU - Pokam-Fosso, Priscille Eunice AU - Atogho-Tiedeu, Barbara AU - Noubiap, Jean Jacques N. AU - Evehe, Marie-Solange AU - Djokam-Dadjeu, Rosine AU - Donfack, Olivier Sontsa AU - Ngwa, Elvis Ndonwi AU - Guewo-Fokeng, Magellan AU - Mbacham, Wilfred F. AU - Sobngwi, Eugene AU - Mbanya, Jean Claude PY - 2016 DA - 2016/05/12 TI - The Pro12Ala polymorphism in the PPAR-γ2 gene is not associated to obesity and type 2 diabetes mellitus in a Cameroonian population JO - BMC Obesity SP - 26 VL - 3 IS - 1 AB - Peroxisome proliferator-activated receptor gamma 2 (PPAR-γ2) is a transcription factor with a key role in adipocyte differentiation, lipid storage and glucose homeostasis. The Ala allele of the common Pro12Ala polymorphism in the isoform PPAR-γ2 is at the center of many controversies because in some populations, it has been observed to be associated with T2DM or obesity but, not in others. The aim of this study was to investigate the association of Pro12Ala polymorphism in the PPAR-γ2 gene with susceptibility to obesity or T2DM in a Cameroonian population. SN - 2052-9538 UR - https://doi.org/10.1186/s40608-016-0104-6 DO - 10.1186/s40608-016-0104-6 ID - Mato2016 ER -