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Table 2 Test properties for different levels of hepatorenal index for the prediction of insulin resistance (HOMA1-IR)

From: Hepatic steatosis, detected by hepatorenal index in ultrasonography, as a predictor of insulin resistance in obese subjects

HOMA-IR >2.3
  All participants (n = 85)
(n = 21 with HOMA-IR >2.3)
BMI ≥30 (n = 45)
(n = 18 with HOMA-IR >2.3)
BMI ≥35 (n = 27)
(n = 15 with HOMA-IR >2.3)
HRI cut-off 1.17 1.42 1.17 1.42 1.17 1.42
Sensitivity 0.90 (.71; .97) 0.33 (.17; .55) 0.94 (.74; .99) 0.33 (.16; .56) 0.93 (.70; .99) 0.27 (.11; .52)
Specificity 0.70 (.58; .80) 0.94 (.85; .98) 0.70 (.52; .84) 0.96 (.82; .99) 0.75 (.47; .91) 0.92 (.65; 99)
LR + 3.05 (2.04; 4.56) 5.33 (1.73; 16.4) 3.19 (1.76; 5.76) 9.0 (1.18; 68.6) 3.73 (1.39; 10.0) 3.20 (.41; 25.0)
LR - 0.14 (.04; .51) 0.71 (.52; .97) 0.08 (.01; .54) 0.69 (.50; .97) 0.09 (.01; .61) 0.80 (.56; 1.14)
HOMA-IR >2.5
  All participants (n = 85)
(n = 17 with HOMA-IR >2.5)
BMI ≥30 (n = 45)
(n = 14 with HOMA-IR >2.5)
BMI ≥35 (n = 27)
(n = 12 with HOMA-IR >2.5)
HRI cut-off 1.17 1.42 1.17 1.42 1.17 1.42
Sensitivity 0.88 (.66; .97) 0.29 (.13; .53) 0.93 (.69; .99) 0.29 (.12; .55) 0.92 (.56; .99) 0.18 (.05; .48)
Specificity 0.66 (.54; .76) 0.94 (.82; .94) 0.61 (.44; 76) 0.90 (.75; 97) 0.60 (.36; .80) 0.81 (.57; .93)
LR + 2.61 (1.79; 3.80) 4.85 (1.15; 9.63) 2.40 (1.51; 3.82) 2.95 (.76; 11.4) 2.29 (1.21; 4.36) 0.97 (.19; 4.88)
LR - 0.18 (.05; .66) 0.75 (.57; 1.06) 0.12 (.02; 79) 0.79 (.56; 1.12) 0.14 (.02; 95) 1.01 (.70; 1.45)
  1. Test properties and likelihood ratios (LR ±) for different cut-off values of hepatorenal index (HRI) for predicting different levels of insulin resistance, defined by Homeostasis Model Assessment of Insulin Resistance (HOMA1-IR) >2.3 and 2.5, respectively. BMI subgroups are analysed specifically