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Table 2 Test properties for different levels of hepatorenal index for the prediction of insulin resistance (HOMA1-IR)

From: Hepatic steatosis, detected by hepatorenal index in ultrasonography, as a predictor of insulin resistance in obese subjects

HOMA-IR >2.3

 

All participants (n = 85)

(n = 21 with HOMA-IR >2.3)

BMI ≥30 (n = 45)

(n = 18 with HOMA-IR >2.3)

BMI ≥35 (n = 27)

(n = 15 with HOMA-IR >2.3)

HRI cut-off

1.17

1.42

1.17

1.42

1.17

1.42

Sensitivity

0.90 (.71; .97)

0.33 (.17; .55)

0.94 (.74; .99)

0.33 (.16; .56)

0.93 (.70; .99)

0.27 (.11; .52)

Specificity

0.70 (.58; .80)

0.94 (.85; .98)

0.70 (.52; .84)

0.96 (.82; .99)

0.75 (.47; .91)

0.92 (.65; 99)

LR +

3.05 (2.04; 4.56)

5.33 (1.73; 16.4)

3.19 (1.76; 5.76)

9.0 (1.18; 68.6)

3.73 (1.39; 10.0)

3.20 (.41; 25.0)

LR -

0.14 (.04; .51)

0.71 (.52; .97)

0.08 (.01; .54)

0.69 (.50; .97)

0.09 (.01; .61)

0.80 (.56; 1.14)

HOMA-IR >2.5

 

All participants (n = 85)

(n = 17 with HOMA-IR >2.5)

BMI ≥30 (n = 45)

(n = 14 with HOMA-IR >2.5)

BMI ≥35 (n = 27)

(n = 12 with HOMA-IR >2.5)

HRI cut-off

1.17

1.42

1.17

1.42

1.17

1.42

Sensitivity

0.88 (.66; .97)

0.29 (.13; .53)

0.93 (.69; .99)

0.29 (.12; .55)

0.92 (.56; .99)

0.18 (.05; .48)

Specificity

0.66 (.54; .76)

0.94 (.82; .94)

0.61 (.44; 76)

0.90 (.75; 97)

0.60 (.36; .80)

0.81 (.57; .93)

LR +

2.61 (1.79; 3.80)

4.85 (1.15; 9.63)

2.40 (1.51; 3.82)

2.95 (.76; 11.4)

2.29 (1.21; 4.36)

0.97 (.19; 4.88)

LR -

0.18 (.05; .66)

0.75 (.57; 1.06)

0.12 (.02; 79)

0.79 (.56; 1.12)

0.14 (.02; 95)

1.01 (.70; 1.45)

  1. Test properties and likelihood ratios (LR ±) for different cut-off values of hepatorenal index (HRI) for predicting different levels of insulin resistance, defined by Homeostasis Model Assessment of Insulin Resistance (HOMA1-IR) >2.3 and 2.5, respectively. BMI subgroups are analysed specifically