|
Variable
|
LLLT (N = 15)
|
Lorcaserin (N = 14)
|
Combination (N = 13a)
|
|---|
|
RBC
|
|
Baseline
|
4.59 ± 0.32
|
4.75 ± 0.43
|
4.80 ± 0.41
|
|
Week 12
|
4.61 ± 0.29
|
4.70 ± 0.42
|
4.65 ± 0.34
|
|
Delta
|
+0.01 ± 0.20
|
−0.06 ± 0.17
|
−0.15 ± 0.26
|
|
Hemoglobin
|
|
Baseline
|
13.77 ± 0.92
|
14.34 ± 1.26
|
14.00 ± 1.26
|
|
Week 12
|
13.83 ± 0.81
|
14.08 ± 1.28
|
13.55 ± 1.15
|
|
Delta
|
+0.07 ± 0.57
|
−0.26 ± 0.61
|
−0.45 ± 0.86
|
|
Hematocrit
|
|
Baseline
|
41.35 ± 2.07
|
42.81 ± 3.00
|
42.17 ± 2.82
|
|
Week 12
|
41.53 ± 2.13
|
42.03 ± 2.92
|
40.78 ± 2.67
|
|
Delta
|
+0.17 ± 1.82
|
−0.77 ± 1.93
|
−1.39 ± 2.37
|
|
MCV
|
|
Baseline
|
90.19 ± 4.38
|
90.21 ± 3.18
|
88.09 ± 4.07
|
|
Week 12
|
90.29 ± 3.69
|
89.66 ± 3.76
|
87.86 ± 4.00
|
|
Delta
|
+0.10 ± 2.05
|
−0.56 ± 2.08
|
−0.23 ± 1.86
|
|
RDW
|
|
Baseline
|
13.23 ± 0.74
|
13.11 ± 0.50
|
13.41 ± 0.61
|
|
Week 12
|
13.19 ± 0.58
|
12.96 ± 0.49
|
13.22 ± 0.69
|
|
Delta
|
−0.04 ± 0.40
|
−0.14 ± 0.37
|
−0.19 ± 0.48
|
|
WBC
|
|
Baseline
|
6.83 ± 1.71
|
7.20 ± 1.45
|
6.98 ± 1.28
|
|
Week 12
|
5.99 ± 1.41
|
6.81 ± 2.11
|
6.32 ± 1.57
|
|
Delta
|
−0.83 ± 1.26*
|
−0.39 ± 1.08
|
−0.66 ± 1.11
|
|
Neutrophils
|
|
Baseline
|
4.03 ± 1.58
|
4.15 ± 1.12
|
4.29 ± 1.08
|
|
Week 12
|
3.30 ± 1.10
|
3.99 ± 1.72
|
3.78 ± 1.20
|
|
Delta
|
−0.74 ± 1.17*
|
−0.16 ± 0.99
|
−0.51 ± 0.77*
|
|
Lymphocytes
|
|
Baseline
|
2.04 ± 0.41
|
2.22 ± 0.55
|
2.00 ± 0.39
|
|
Week 12
|
1.93 ± 0.38
|
2.03 ± 0.41
|
1.84 ± 0.53
|
|
Delta
|
−0.11 ± 0.25
|
−0.19 ± 0.43
|
−0.16 ± 0.39
|
|
Monocytes
|
|
Baseline
|
0.51 ± 0.13
|
0.60 ± 0.19
|
0.49 ± 0.13
|
|
Week 12
|
0.47 ± 0.13
|
0.58 ± 0.22
|
0.47 ± 0.10
|
|
Delta
|
−0.05 ± 0.12
|
−0.02 ± 0.12
|
−0.03 ± 0.06
|
|
Eosinophils
|
|
Baseline
|
0.22 ± 0.12
|
0.18 ± 0.11
|
0.16 ± 0.05
|
|
Week 12
|
0.26 ± 0.18
|
0.17 ± 0.11
|
0.19 ± 0.15
|
|
Delta
|
+0.04 ± 0.11
|
−0.01 ± 0.06
|
+0.03 ± 0.15
|
|
Basophils
|
|
Baseline
|
0.03 ± 0.02
|
0.04 ± 0.03
|
0.03 ± 0.02
|
|
Week 12
|
0.04 ± 0.02
|
0.04 ± 0.03
|
0.03 ± 0.01
|
|
Delta
|
+0.01 ± 0.02
|
−0.00 ± 0.02
|
+0.00 ± 0.01
|
|
Platelets
|
|
Baseline
|
251.4 ± 56.6
|
287.0 ± 69.3
|
292.9 ± 60.3
|
|
Week 12
|
253.4 ± 51.2
|
277.1 ± 70.9
|
287.4 ± 47.7
|
|
Delta
|
+2.0 ± 20.8
|
−9.9 ± 27.3
|
−5.5 ± 26.0
|
-
*p < 0.05, for paired t-test comparing week 12 versus baseline
-
aOf the 15 subjects assigned to the combination group, 2 discontinued prior to week 12 and are not included in the analysis
