A randomized, open-label pilot of the combination of low-level laser therapy and lorcaserin for weight loss

Croghan, Ivana T.; Ebbert, Jon O.; Schroeder, Darrell R.; Hurt, Ryan T.; Hagstrom, Victoria; Clark, Matthew M.

doi:10.1186/s40608-016-0122-4

BMC Obesity

Table 4 Lab values

From: A randomized, open-label pilot of the combination of low-level laser therapy and lorcaserin for weight loss

Variable	LLLT (N = 15)	Lorcaserin (N = 14)	Combination (N = 13^a)
RBC
Baseline	4.59 ± 0.32	4.75 ± 0.43	4.80 ± 0.41
Week 12	4.61 ± 0.29	4.70 ± 0.42	4.65 ± 0.34
Delta	+0.01 ± 0.20	−0.06 ± 0.17	−0.15 ± 0.26
Hemoglobin
Baseline	13.77 ± 0.92	14.34 ± 1.26	14.00 ± 1.26
Week 12	13.83 ± 0.81	14.08 ± 1.28	13.55 ± 1.15
Delta	+0.07 ± 0.57	−0.26 ± 0.61	−0.45 ± 0.86
Hematocrit
Baseline	41.35 ± 2.07	42.81 ± 3.00	42.17 ± 2.82
Week 12	41.53 ± 2.13	42.03 ± 2.92	40.78 ± 2.67
Delta	+0.17 ± 1.82	−0.77 ± 1.93	−1.39 ± 2.37
MCV
Baseline	90.19 ± 4.38	90.21 ± 3.18	88.09 ± 4.07
Week 12	90.29 ± 3.69	89.66 ± 3.76	87.86 ± 4.00
Delta	+0.10 ± 2.05	−0.56 ± 2.08	−0.23 ± 1.86
RDW
Baseline	13.23 ± 0.74	13.11 ± 0.50	13.41 ± 0.61
Week 12	13.19 ± 0.58	12.96 ± 0.49	13.22 ± 0.69
Delta	−0.04 ± 0.40	−0.14 ± 0.37	−0.19 ± 0.48
WBC
Baseline	6.83 ± 1.71	7.20 ± 1.45	6.98 ± 1.28
Week 12	5.99 ± 1.41	6.81 ± 2.11	6.32 ± 1.57
Delta	−0.83 ± 1.26^*	−0.39 ± 1.08	−0.66 ± 1.11
Neutrophils
Baseline	4.03 ± 1.58	4.15 ± 1.12	4.29 ± 1.08
Week 12	3.30 ± 1.10	3.99 ± 1.72	3.78 ± 1.20
Delta	−0.74 ± 1.17^*	−0.16 ± 0.99	−0.51 ± 0.77^*
Lymphocytes
Baseline	2.04 ± 0.41	2.22 ± 0.55	2.00 ± 0.39
Week 12	1.93 ± 0.38	2.03 ± 0.41	1.84 ± 0.53
Delta	−0.11 ± 0.25	−0.19 ± 0.43	−0.16 ± 0.39
Monocytes
Baseline	0.51 ± 0.13	0.60 ± 0.19	0.49 ± 0.13
Week 12	0.47 ± 0.13	0.58 ± 0.22	0.47 ± 0.10
Delta	−0.05 ± 0.12	−0.02 ± 0.12	−0.03 ± 0.06
Eosinophils
Baseline	0.22 ± 0.12	0.18 ± 0.11	0.16 ± 0.05
Week 12	0.26 ± 0.18	0.17 ± 0.11	0.19 ± 0.15
Delta	+0.04 ± 0.11	−0.01 ± 0.06	+0.03 ± 0.15
Basophils
Baseline	0.03 ± 0.02	0.04 ± 0.03	0.03 ± 0.02
Week 12	0.04 ± 0.02	0.04 ± 0.03	0.03 ± 0.01
Delta	+0.01 ± 0.02	−0.00 ± 0.02	+0.00 ± 0.01
Platelets
Baseline	251.4 ± 56.6	287.0 ± 69.3	292.9 ± 60.3
Week 12	253.4 ± 51.2	277.1 ± 70.9	287.4 ± 47.7
Delta	+2.0 ± 20.8	−9.9 ± 27.3	−5.5 ± 26.0

^*p < 0.05, for paired t-test comparing week 12 versus baseline
^aOf the 15 subjects assigned to the combination group, 2 discontinued prior to week 12 and are not included in the analysis

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