Association of gene coding variation and resting metabolic rate in a multi-ethnic sample of children and adults

Hellwege, Jacklyn N.; Velez Edwards, Digna R.; Acra, Sari; Chen, Kong; Buchowski, Maciej S.; Edwards, Todd L.

doi:10.1186/s40608-017-0145-5

BMC Obesity

Table 5 Genetically predicted gene expression results from MetaXcan with RMR genetic association data

From: Association of gene coding variation and resting metabolic rate in a multi-ethnic sample of children and adults

Gene	Z-score	P-value	r²	Tissue
UHMK1	4.01	5.96E-05	0.056	Nerve-Tibial
ZNF506	−3.84	0.00012	0.021	Skin-SunExposed
B3GNT6	−3.80	0.00014	0.18	Brain_Hippocampus
RTN2	3.74	0.00018	0.028	Brain_Hypothalamus
ZNF682	−3.72	0.00019	0.025	Colon_Sigmoid
RAB5C	−3.67	0.00024	0.023	Heart_AtrialAppendage
UBN2	−3.66	0.00026	0.048	Artery_Aorta
GALC	3.65	0.00026	0.051	Brain_Cortex
SPATA7	−3.65	0.00026	0.012	Pituitary
ZC3HAV1L	3.64	0.00027	0.062	Stomach
FAR1	−3.63	0.00028	0.015	Brain_Anteriorcingulatecortex
PVALB	−3.62	0.00030	0.026	Artery_Aorta
PVALB	3.62	0.00030	0.079	Brain_CerebellarHemisphere
FMO5	3.55	0.00038	0.13	Adrenal
ACP6	3.55	0.00038	0.00037	Brain_CerebellarHemisphere
ACP6	3.55	0.00038	0.47	Brain_Cortex
ACP6	3.55	0.00038	0.39	Brain_FrontalCortex
ACP6	3.55	0.00038	0.23	Brain_Hippocampus
ACP6	3.55	0.00038	0.43	Brain_Putamen_basalganglia
ACP6	3.55	0.00038	0.36	Cells_fibroblasts
ACP6	3.55	0.00038	0.26	Colon_Sigmoid
ACP6	3.55	0.00038	0.40	Colon_tranverse
ACP6	3.55	0.00038	0.34	Esophagus_GastroesophagealJunction
ACP6	3.55	0.00038	0.37	Esophagus_Muscularis
ACP6	3.55	0.00038	0.57	Pituitary
ACP6	3.55	0.00038	0.12	SmallIntestine
ACP6	3.55	0.00038	0.39	Stomach
ACP6	3.55	0.00038	0.48	Testis
ACP6	3.55	0.00038	0.52	Thyroid
BCL9	3.55	0.00038	0.0050	WholeBlood
ACP6	3.53	0.00041	0.17	Brain_Cerebellum
RP11-345 J4.3	−3.52	0.00043	0.052	Artery_Tibial
HABP2	−3.49	0.00048	0.012	Esophagus_GastroesophagealJunction
KRT38	3.49	0.00048	0.28	WholeBlood
GPX8	−3.49	0.00048	0.00093	Pituitary
PPAP2A	−3.49	0.00048	0.0018	Spleen
ZNF169	−3.49	0.00048	0.031	Brain_Cerebellum
BARX1	3.49	0.00048	0.021	Brain_Cortex
PTPDC1	−3.49	0.00048	0.040	Esophagus_GastroesophagealJunction

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