|
Effect1
|
AGPAT9
|
FABP4
|
C/EBPα
|
C/EBPβ
|
KLF7
|
PPARγ
|
MGLL
|
SREBP1
|
|
Diet
|
|
HC
|
0.44
|
1.06a
|
0.35
|
1.77
|
1.31
|
0.45
|
2.60
|
0.51
|
|
HF
|
0.36
|
1.00ab
|
0.32
|
1.40
|
1.32
|
0.50
|
2.21
|
0.43
|
|
HP
|
0.36
|
0.84b
|
0.32
|
1.33
|
1.19
|
0.39
|
2.31
|
0.41
|
|
SEM
|
0.04
|
0.06
|
0.02
|
0.18
|
0.09
|
0.04
|
0.27
|
0.04
|
|
P-value
|
0.23
|
0.02
|
0.37
|
0.21
|
0.66
|
0.27
|
0.55
|
0.10
|
|
Fed
|
0.57a
|
1.03
|
0.51a
|
1.00b
|
1.28b
|
0.73a
|
2.42
|
0.67a
|
|
Fasted
|
0.31b
|
0.96
|
0.16c
|
2.26a
|
1.59a
|
0.32b
|
2.54
|
0.39b
|
|
Refed
|
0.31b
|
0.91
|
0.33b
|
1.18b
|
0.97c
|
0.32b
|
2.18
|
0.33b
|
|
SEM
|
0.04
|
0.05
|
0.02
|
0.17
|
0.09
|
0.04
|
0.26
|
0.04
|
|
P-value
|
0.0001
|
0.35
|
0.0001
|
0.0001
|
0.0001
|
0.0001
|
0.57
|
0.0001
|
|
D × T
|
0.13
|
0.22
|
0.003
|
0.31
|
0.77
|
0.21
|
0.67
|
0.06
|
|
Effect1
|
GATA2
|
ATGL
|
PLN1
|
CGI-58
|
ACADL
|
NPY
|
NPYR2
|
LPL
|
|
Diet
|
|
HC
|
0.97
|
1.41
|
0.89
|
1.24
|
0.70
|
0.91
|
0.69
|
1.21
|
|
HF
|
1.05
|
1.42
|
0.77
|
0.70
|
0.56
|
0.64
|
0.66
|
1.41
|
|
HP
|
0.86
|
1.36
|
0.87
|
0.96
|
0.49
|
1.09
|
0.61
|
1.64
|
|
SEM
|
0.07
|
0.17
|
0.13
|
0.19
|
0.15
|
0.26
|
0.05
|
0.19
|
|
P-value
|
0.11
|
0.96
|
0.76
|
0.15
|
0.57
|
0.46
|
0.48
|
0.30
|
|
Treatment
|
|
Fed
|
1.10
|
1.50
|
0.79
|
1.20
|
0.72
|
1.35
|
0.89a
|
1.55
|
|
Fasted
|
0.90
|
1.38
|
1.00
|
0.93
|
0.76
|
0.85
|
0.56b
|
1.25
|
|
Refed
|
0.89
|
1.31
|
0.74
|
0.77
|
0.28
|
0.44
|
0.50b
|
1.47
|
|
SEM
|
0.06
|
0.17
|
0.13
|
0.19
|
0.15
|
0.26
|
0.05
|
0.19
|
|
P-value
|
0.08
|
0.76
|
0.30
|
0.29
|
0.03
|
0.07
|
0.0001
|
0.50
|
|
D × T
|
0.26
|
0.76
|
0.56
|
0.51
|
0.14
|
0.76
|
0.03
|
0.37
|
-
1Values represent least squares means and pooled standard errors of the means with associated P-values for each effect. D × T: interaction between diet (D) and treatment (T). Different superscipts within an effect for each gene are significantly different at P < 0.05, Tukey’s test. Abbreviations: 1-acylglycerol-3-phosphate O-acyltransferase 9: AGPAT9; Fatty acid binding protein 4: FABP4; CCAAT/enhancer-binding protein alpha and beta: C/EBPα and C/EBPβ, respectively; Krüppel-like factor 7: KLF7; Peroxisome proliferator-activated receptor gamma: PPARγ; Monoglyceride lipase: MGLL; Sterol regulatory element-binding transcription factor 1: SREBP1; GATA-binding protein 2: GATA2; Adipose triglyceride lipase: ATGL; Perilipin 1: PLN1; Comparative gene identification-58: CGI-58; Acyl-CoA dehydrogenase, long chain: ACADL; Neuropeptide Y: NPY; NPY receptor 2: NPYR2; Lipoprotein lipase: LPL
