|
Effect1
|
AGPAT9
|
FABP4
|
C/EBPα
|
C/EBPβ
|
KLF7
|
PPARγ
|
MGLL
|
SREBP1
|
|
Diet
|
|
HC
|
0.39
|
0.74
|
0.36
|
2.07a
|
1.62ab
|
0.38
|
4.27a
|
0.43
|
|
HF
|
0.34
|
0.75
|
0.36
|
1.50ab
|
1.63a
|
0.41
|
3.33ab
|
0.43
|
|
HP
|
0.34
|
0.71
|
0.40
|
1.10b
|
1.33b
|
0.42
|
2.86b
|
0.38
|
|
SEM
|
0.03
|
0.05
|
0.03
|
0.17
|
0.08
|
0.03
|
0.38
|
0.03
|
|
P-value
|
0.43
|
0.90
|
0.56
|
0.0006
|
0.02
|
0.72
|
0.03
|
0.15
|
|
Treatment
|
|
Fed
|
0.42a
|
0.69
|
0.50a
|
1.21b
|
1.32b
|
0.55a
|
4.16a
|
0.64a
|
|
Fasted
|
0.35ab
|
0.79
|
0.27c
|
1.92a
|
1.91a
|
0.27c
|
5.30a
|
0.36b
|
|
Refed
|
0.30b
|
0.72
|
0.36b
|
1.48ab
|
1.32b
|
0.41b
|
1.03b
|
0.26c
|
|
SEM
|
0.03
|
0.05
|
0.02
|
0.16
|
0.08
|
0.03
|
0.38
|
0.03
|
|
P-value
|
0.02
|
0.30
|
0.0001
|
0.01
|
0.0001
|
0.0001
|
0.0001
|
0.0001
|
|
D × T
|
1.00
|
0.41
|
0.37
|
0.46
|
0.18
|
0.16
|
0.11
|
0.16
|
|
Effect1
|
GATA2
|
ATGL
|
PLN1
|
CGI-58
|
ACADL
|
NPY
|
NPYR2
|
LPL
|
|
Diet
|
|
HC
|
0.77
|
1.42
|
0.78
|
0.55
|
0.65ab
|
0.73
|
0.30
|
1.51
|
|
HF
|
0.88
|
0.74
|
0.56
|
0.74
|
0.55b
|
1.02
|
0.30
|
1.55
|
|
HP
|
0.67
|
0.50
|
0.68
|
0.58
|
0.86a
|
1.03
|
0.31
|
1.60
|
|
SEM
|
0.07
|
0.41
|
0.13
|
0.07
|
0.09
|
0.14
|
0.04
|
0.21
|
|
P-value
|
0.14
|
0.25
|
0.47
|
0.18
|
0.04
|
0.24
|
1.00
|
0.86
|
|
Treatment
|
|
Fed
|
0.80
|
0.60
|
0.58
|
0.63
|
0.67
|
1.49a
|
0.33ab
|
1.67
|
|
Fasted
|
0.78
|
0.66
|
0.74
|
0.57
|
0.72
|
0.84b
|
0.36a
|
1.52
|
|
Refed
|
0.74
|
1.41
|
0.71
|
0.67
|
0.67
|
0.44b
|
0.21c
|
1.56
|
|
SEM
|
0.08
|
0.41
|
0.12
|
0.07
|
0.09
|
0.15
|
0.04
|
0.22
|
|
P-value
|
0.83
|
0.29
|
0.63
|
0.68
|
0.89
|
0.0005
|
0.04
|
0.89
|
|
D × T
|
0.97
|
0.18
|
0.24
|
0.02
|
0.12
|
0.48
|
0.03
|
0.66
|
-
1Values represent least squares means and pooled standard errors of the means with associated P-values for each effect. D × T: interaction between diet (D) and treatment (T). Different superscipts within an effect for each gene are significantly different at P < 0.05, Tukey’s test. Abbreviations: 1-acylglycerol-3-phosphate O-acyltransferase 9: AGPAT9; Fatty acid binding protein 4: FABP4; CCAAT/enhancer-binding protein alpha and beta: C/EBPα and C/EBPβ, respectively; Krüppel-like factor 7: KLF7; Peroxisome proliferator-activated receptor gamma: PPARγ; Monoglyceride lipase: MGLL; Sterol regulatory element-binding transcription factor 1: SREBP1; GATA-binding protein 2: GATA2; Adipose triglyceride lipase: ATGL; Perilipin 1: PLN1; Comparative gene identification-58: CGI-58; Acyl-CoA dehydrogenase, long chain: ACADL; Neuropeptide Y: NPY; NPY receptor 2: NPYR2; Lipoprotein lipase: LPL
