Table 1 Patients’ characteristics at the two centers
Oslo University Hospital Aker | Innlandet Hospital Trust Gjøvik | ||||
|---|---|---|---|---|---|
n | n | p-value | |||
Gender (%male) | 62 (29%) | 211 | 28 (20%) | 139 | 0.05# |
Age (years) | 43 (21–61) | 211 | 44 (24–61) | 139 | 0.66* |
Body mass index (kg/m2) | 43 (33–62) | 211 | 42 (35–53) | 139 | 0.09* |
Ethnicity (% Caucasian) | 195 (93%) | 210 | 139 (100%) | 139 | 0.001# |
Irritable bowel syndrome (IBS) | 17/211 (8%) | 211 | 37/139 (26%) | 139 | <0.001# |
IBS-constipation | 3/17 (18%) | 17 | 7/37 (19%) | 37 | 0.48# |
IBS-diarrhea | 2/17 (12%) | 17 | 11/37 (30%) | 37 | |
IBS-mixed | 11/17 (65%) | 17 | 18/37 (49%) | 37 | |
IBS-unsubtyped | 1/17 (6%) | 17 | 1/37 (3%) | 37 | |
Functional bloating | 21/205 (10%) | 205 | 19/138 (14%) | 138 | 0.32# |
Functional constipation | 20/205 (10%) | 205 | 3/135 (2%) | 138 | 0.006# |
Functional diarrhea | 9/206 (4%) | 206 | 4/139 (3%) | 139 | 0.48# |
Smoking | 56/204 (28%) | 204 | 24/139 (17%) | 139 | 0.03# |
Diabetes mellitus | 53/211 (25%) | 211 | 26/139 (19%) | 139 | 0.16# |
Hypothyroidism | 19/211 (9%) | 211 | 17/138 (12%) | 138 | 0.32# |
Fibromyalgia | 20/211 (10%) | 211 | 25/138 (18%) | 138 | 0.02# |
Self-reported psychiatric disorder | 36/211 (17%) | 211 | 29/139 (21%) | 139 | 0.37# |
Hemoglobin (g/dl) | 14.1 (1.1) | 211 | 14.5 (1.1) | 136 | 0.006 |
White-cell count (×109/l) | 7.4 (2.4–13.3) | 210 | 7.5 (4.2–16.1) | 136 | 0.95* |
Platelet count (×109/l) | 275 (112–519) | 210 | 276 (131–939) | 134 | 0.46* |
HbA1C (%) | 5.8 (4.7–14.9) | 211 | 5.5 (4.5–11.5) | 136 | <0.001* |
Bilirubin (μmol/l) | 7 (2–23) | 210 | 6 (2–28) | 136 | 0.07* |
C-reactive protein (mg/l) | 7 (1–50) | 210 | 5 (0–43) | 136 | 0.01* |
Cholesterol (mmol/l) | 4.9 (1.0) | 210 | 5.1 (1.0) | 136 | 0.10 |
High-density lipoprotein (mmol/l) | 1.1 (0.5–2.0) | 210 | 1.1 (0.4–2.2) | 136 | 0.70* |
Low-density lipoprotein (mmol/l) | 3.1 (0.9) | 210 | 3.3 (0.9) | 136 | 0.02 |
Thyroid stimulating hormone (mIE/l) | 1.4 (0–14.6) | 210 | 1.7 (0–6.9) | 136 | 0.11* |
Free T4 (pmol/l) | 15 (11–28) | 210 | 15 (10–26) | 136 | 0.30* |
Vitamin B1 (nmol/l) | 156 (62–239) | 210 | 153 (104–246) | 135 | 0.70* |
Vitamin B6 (nmol/l) | 29 (5–231) | 211 | 22 (5–209) | 133 | 0.01* |
Vitamin B12 (pmol/l) | 344 (158–1480) | 211 | 346 (158–1401) | 136 | 0.80* |
Folic acid (nmol/l) | 18 (6–46) | 211 | 17 (7–46) | 136 | 0.14* |
Use of statins | 35/211 (17%) | 211 | 19/138 (14%) | 138 | 0.48# |
Use of thyroid substitution therapy | 19/211 (9%) | 211 | 13/139 (9%) | 139 | 0.91# |