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Table 5 Primary analysis 2 - Estimated correlations between change from pre- to post- LGBS in each of biochemical liver function tests, non-invasive ICG clearance

From: Reversal of fibrosis in patients with nonalcoholic steatohepatosis after gastric bypass surgery

Change from pre- to post- LGBS in each of the following test Pearson correlation
Number (99.83% CI) P-value
ICG K value AST 19 −0.04 (−0.68, 0.63) 0.88
ALT 19 0.01 (−0.65, 0.66) 0.98
Alkaline phosphatase 19 −0.09 (−0.71, 0.60) 0.70
Total bilirubin 19 0.07 (−0.61, 0.70) 0.76
Albumin 19 0.30 (−0.44, 0.80) 0.21
PT 17 −0.24 (−0.80, 0.53) 0.35
PTT 5 −0.41 (−0.99, 0.95) 0.49
   Spearman correlation
Fibrosis AST 12 −0.23 (−1.00, 0.72) 0.47
ALT 12 0.28 (−0.67, 1.00) 0.38
Alkaline phosphatase 12 0.33 (−0.61, 1.00) 0.29
Total bilirubin 12 −0.54 (−1.00, 0.41) 0.07
Albumin 12 0.03 (−0.91, 0.98) 0.92
PT 13 −0.35 (−1.00, 0.55) 0.24
PTT 4 0.45 (−1.00. 1.00) 0.55
ICG K value 8 0.38 (−0.80, 1.00) 0.35
  1. AST Aspartate transaminase, ALT Alanine transaminase, ICG Indocyanine green, NAS Non-alcoholic steatohepatitis, PT Prothrombin time, PTT Partial Thromboplastin Time
  2. P-value for testing the null hypothesis that correlation is zero. The significance criterion was P < 0.0017 (i.e.,0.025/15; Bonferroni correction)