Reversal of fibrosis in patients with nonalcoholic steatohepatosis after gastric bypass surgery

BMC Obesity

Table 5 Primary analysis 2 - Estimated correlations between change from pre- to post- LGBS in each of biochemical liver function tests, non-invasive ICG clearance

Change from pre- to post- LGBS in each of the following test		Pearson correlation
		Number	(99.83% CI)^†	P-value^†
ICG K value	AST	19	−0.04 (−0.68, 0.63)	0.88
	ALT	19	0.01 (−0.65, 0.66)	0.98
	Alkaline phosphatase	19	−0.09 (−0.71, 0.60)	0.70
	Total bilirubin	19	0.07 (−0.61, 0.70)	0.76
	Albumin	19	0.30 (−0.44, 0.80)	0.21
	PT	17	−0.24 (−0.80, 0.53)	0.35
	PTT	5	−0.41 (−0.99, 0.95)	0.49
		Spearman correlation
Fibrosis	AST	12	−0.23 (−1.00, 0.72)	0.47
	ALT	12	0.28 (−0.67, 1.00)	0.38
	Alkaline phosphatase	12	0.33 (−0.61, 1.00)	0.29
	Total bilirubin	12	−0.54 (−1.00, 0.41)	0.07
	Albumin	12	0.03 (−0.91, 0.98)	0.92
	PT	13	−0.35 (−1.00, 0.55)	0.24
	PTT	4	0.45 (−1.00. 1.00)	0.55
	ICG K value	8	0.38 (−0.80, 1.00)	0.35

AST Aspartate transaminase, ALT Alanine transaminase, ICG Indocyanine green, NAS Non-alcoholic steatohepatitis, PT Prothrombin time, PTT Partial Thromboplastin Time
^† P-value for testing the null hypothesis that correlation is zero. The significance criterion was P < 0.0017 (i.e.,0.025/15; Bonferroni correction)

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