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Table 2 Comparisons between obese and non-obese, users and non-users of antihypertensive and lipid-lowering drugs

From: Abdominal obesity in type 1 diabetes associated with gender, cardiovascular risk factors and complications, and difficulties achieving treatment targets: a cross sectional study at a secondary care diabetes clinic

  Abdominal obesity Anti-hypertensive drugs Lipid-lowering drugs
Yes No P a Yes No P a Yes No P a
N 49 (17) 235 (83)   95 (33) 189 (67)   133 (47) 151 (53)  
Age 45 (35, 53) 42 (31, 51) 0.11 b 49 (42, 56) 39 (28, 56) < 0.001 b 49 (42, 54) 34 (27, 44) < 0.001 b
Diabetes duration 22 (14, 28) 20 (11, 31) 0.64b 29 (20, 35) 16 (9, 25) < 0.001 b 26 (14, 34) 17 (9, 24) < 0.001 b
Abdominal obesity 49 (100) 0   22 (23) 27 (14) 0.069 31 (23) 18 (12) 0.012
HbA1c > 52 mmol/mol (>  6.9%) 45 (92) 185 (79) 0.044 79 (83) 151 (80) 0.63 114 (86) 116 (77) 0.069
HbA1c > 70 mmol/mol (>  8.6%) 24 (49) 54 (23) < 0.001 29 (30) 49 (26) 0.48 40 (30) 38 (25) 0.42
TC (mmol/l) 4.7 (4.2, 5.8) 4.6 (4.1, 5.1) 0.047 b 4.5 (4.0, 5.2) 4.6 (4.1, 5.2) 0.32 b
High TC (> 4.5 mmol/l) 29 (59) 120 (51) 0.35 63 (47) 86 (57) 0.12
Triglycerides (mmol/l) 1.2 (0.8, 1.9) 0.9 (0.7, 1.1) < 0.001 b 1.0 (0.7, 1.3) 0.8 (0.7, 1.1) 0.014 b
High triglycerides (≥ 1.7 mmol/l) 14 (29) 20 (8) < 0.001 21 (16) 13 (9) 0.070
HDL (mmol/l) 1.5 (1.3, 1.7) 1.5 (1.3, 1.8) 0.47 b 1.5 (1.3, 1.8) 1.5 (1.3, 1.8) 0.48 b
Low HDL (m/w:< 1.04/1.29 mmol/l) 5 (10) 27 (11) > 0.99 12 (9) 20 (13) 0.35
LDL (mmol/l) 3.2 (2.5, 3.8) 2.8 (2.4, 3.3) 0.021 b 2.7 (2.3, 3.3) 3.0 (2.5, 3.4) 0.058 b
High LDL (> 2.5 mmol/l) 36 (74) 146 (62) 0.14 74 (56) 108 (72) 0.006
Hs-CRP c (mg/l) 2.5 (0.6, 4.6) 0.6 (0.2, 1.4) < 0.001 b 0.6 (0.3, 1.7) 0.7 (0.3, 1.9) 0.87 0.6 (0.3, 1.8) 0.8 (0.3, 1.7) 0.97
SBP (mm Hg) 130 (120, 132) 120 (110, 130) 0.004 b 130 (125, 135) 120 (110, 125) < 0.001 b
High SBP (> 130 mmHg) 24 (49) 76 (32) 0.033 59 (62) 41 (22) < 0.001
DBP (mm Hg) 70 (70, 78) 70 (65, 75) 0.051 b 70 (70, 78) 70 (65, 75) 0.011 b
High DBP (>  80 mmHg) 5 (10) 8 (3) 0.054 7 (7) 6 (3) 0.14
Hypoglycemia (severe episodes) 3 (6) 10 (4) 0.48
Smoking 4 (9) 24 (11) 0.80 6 (6) 22 (12) 0.20 13 (10) 15 (10) > 0.99
Physical inactivity (<  1/week) 9 (19) 22 (10) 0.084 10 (11) 21 (12) > 0.99 11 (8) 20 (14) 0.18
CV complications 5 (10) 5 (2) 0.016 7 (7) 3 (2) 0.018 9 (7) 1 (1) 0.007
LLD 31 (63) 102 (43) 0.012 62 (65) 71 (38) < 0.001
AHD 22 (45) 73 (31) 0.069 62 (47) 33 (22) < 0.001
MDII and OAD 13 (27) 4 (2) < 0.001
CSII 1 (2) 25 (10)  
MDII 35 (71) 206 (88)  
Reached all treatment targets 0 19 (8) 0.052
  1. Data are n (%) or median (q1, q3)
  2. a Fisher’s exact test unless otherwise indicated. b Mann-Whitney U test. c Missing values for abdominal obesity/no abdominal obesity: N = 27 (55%)/86 (37%)