Contrast
|
Treatment
|
N
|
LS Mean (SE)
|
LS Mean Difference (SE)
|
P Value
|
---|
Without Baseline Covariates
|
Capsimax 2 mg vs Placebo
|
Capsimax 2 mg
|
27
|
2.44 (2.14)
|
−0.82
|
0.7860
|
Placebo
|
28
|
3.26 (2.10)
|
Capsimax 4 mg vs Placebo
|
Capsimax 4 mg
|
22
|
−0.81 (2.37)
|
−4.07
|
0.2037
|
Placebo
|
28
|
3.26 (2.10)
|
With Baseline Covariates
|
Capsimax 2 mg vs Placebo
|
Capsimax 2 mg
|
26
|
3.45 (2.79)
|
−2.43
|
0.5044
|
Placebo
|
27
|
5.88 (2.76)
|
Capsimax 4 mg vs Placebo
|
Capsimax 4 mg
|
22
|
−0.80 (2.37)
|
−6.68
|
0.0487
|
Placebo
|
27
|
5.88 (2.76)
|
- Analysis “Without Baseline Covariates” was a One-way ANOVA model. Analysis “With Baseline Covariates” was a generalized linear model containing treatment, covariates and treatment x covariate interactions. Two subjects were lost to the “With Baseline Covariates” analysis due to missing values at baseline