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Table 2 Anthropomorphic Measurements

From: A randomized, open-label pilot of the combination of low-level laser therapy and lorcaserin for weight loss

Variable

Treatment group

Estimated treatment effect (90 % C.I.)a

LLLT (N = 15) ± SD

Lorcaserin (N = 14) ± SD

Combination (N = 15b) ± SD

Combination vs. LLLT only

Combination vs. Lorcaserin only

Weight, kg

 Baseline

96.0 ± 15.3

94.4 ± 16.2

90.3 ± 14.0

  

 Week 12

95.0 ± 14.2

90.7 ± 17.4

86.7 ± 14.2

−2.6 (-5.0, -0.3)

+0.1 (-2.3, +2.5)

 Delta

−1.0 ± 4.4

−3.7 ± 3.3c

−3.5 ± 3.6c

P = .070

P = .950

Weight loss of >5 %, n (%)

2 (13)

8 (57)

5 (33)

  

Body Mass Index, kg/m2

 Baseline

33.5 ± 3.9

33.6 ± 5.1

33.4 ± 4.2

  

 Week 12

33.1 ± 3.5

32.3 ± 5.7

32.1 ± 4.3

−1.0 (-1.8, -0.1)

+0.0 (-0.8, +0.9)

 Delta

−0.4 ± 1.5

−1.3 ± 1.2c

−1.3 ± 1.3c

P = .063

P = .973

Waist Circumference, cm

 Baseline

105.3 ± 11.6

108.0 ± 15.7

100.9 ± 10.0

  

 Week 12

103.0 ± 11.3

102.0 ± 16.3

96.9 ± 12.4

−1.8 (-5.4, +1.7)

+1.7 (-1.9, +5.4)

 Delta

−2.3 ± 4.1d

−6.0 ± 7.3c

−4.0 ± 5.5d

P = .398

P = .436

Hip Circumference, cm

 Baseline

119.1 ± 8.8

120.7 ± 12.1

119.0 ± 8.8

  

 Week 12

118.1 ± 8.3

116.2 ± 12.0

116.0 ± 9.3

−2.0 (-3.6, -0.3)

+1.5 (-0.2, +3.2)

 Delta

−1.0 ± 3.1

−4.5 ± 2.1e

−3.0 ± 3.0c

P = .059

P = .159

Waist-to-Hip ratio

 Baseline

0.885 ± 0.086

0.892 ± 0.072

0.850 ± 0.063

  

 Week 12

0.874 ± 0.086

0.874 ± 0.087

0.834 ± 0.068

−0.007 (-0.032, +0.018)

−0.001 (-0.027, +0.025)

 Delta

−0.011 ± 0.035

−0.017 ± 0.053

−0.016 ± 0.032

P = .657

P = .961

  1. CI Confidence Interval, SD Standard Deviation
  2. aEstimated treatment effect from analysis of covariance (ANCOVA) with the baseline value of the given variable included as a covariate
  3. bThere were 2 subjects in the combination group who discontinued prior to week 12 (one after week 2 and one after week 6). For these 2 subjects the last value of each variable was carried forward to week 12
  4. c p < 0.01 for paired t-test comparing week 12 versus baseline
  5. d p < 0.05 for paired t-test comparing week 12 versus baseline
  6. e p < 0.001 for paired t-test comparing week 12 versus baseline