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Table 2 Anthropomorphic Measurements

From: A randomized, open-label pilot of the combination of low-level laser therapy and lorcaserin for weight loss

Variable Treatment group Estimated treatment effect (90 % C.I.)a
LLLT (N = 15) ± SD Lorcaserin (N = 14) ± SD Combination (N = 15b) ± SD Combination vs. LLLT only Combination vs. Lorcaserin only
Weight, kg
 Baseline 96.0 ± 15.3 94.4 ± 16.2 90.3 ± 14.0   
 Week 12 95.0 ± 14.2 90.7 ± 17.4 86.7 ± 14.2 −2.6 (-5.0, -0.3) +0.1 (-2.3, +2.5)
 Delta −1.0 ± 4.4 −3.7 ± 3.3c −3.5 ± 3.6c P = .070 P = .950
Weight loss of >5 %, n (%) 2 (13) 8 (57) 5 (33)   
Body Mass Index, kg/m2
 Baseline 33.5 ± 3.9 33.6 ± 5.1 33.4 ± 4.2   
 Week 12 33.1 ± 3.5 32.3 ± 5.7 32.1 ± 4.3 −1.0 (-1.8, -0.1) +0.0 (-0.8, +0.9)
 Delta −0.4 ± 1.5 −1.3 ± 1.2c −1.3 ± 1.3c P = .063 P = .973
Waist Circumference, cm
 Baseline 105.3 ± 11.6 108.0 ± 15.7 100.9 ± 10.0   
 Week 12 103.0 ± 11.3 102.0 ± 16.3 96.9 ± 12.4 −1.8 (-5.4, +1.7) +1.7 (-1.9, +5.4)
 Delta −2.3 ± 4.1d −6.0 ± 7.3c −4.0 ± 5.5d P = .398 P = .436
Hip Circumference, cm
 Baseline 119.1 ± 8.8 120.7 ± 12.1 119.0 ± 8.8   
 Week 12 118.1 ± 8.3 116.2 ± 12.0 116.0 ± 9.3 −2.0 (-3.6, -0.3) +1.5 (-0.2, +3.2)
 Delta −1.0 ± 3.1 −4.5 ± 2.1e −3.0 ± 3.0c P = .059 P = .159
Waist-to-Hip ratio
 Baseline 0.885 ± 0.086 0.892 ± 0.072 0.850 ± 0.063   
 Week 12 0.874 ± 0.086 0.874 ± 0.087 0.834 ± 0.068 −0.007 (-0.032, +0.018) −0.001 (-0.027, +0.025)
 Delta −0.011 ± 0.035 −0.017 ± 0.053 −0.016 ± 0.032 P = .657 P = .961
  1. CI Confidence Interval, SD Standard Deviation
  2. aEstimated treatment effect from analysis of covariance (ANCOVA) with the baseline value of the given variable included as a covariate
  3. bThere were 2 subjects in the combination group who discontinued prior to week 12 (one after week 2 and one after week 6). For these 2 subjects the last value of each variable was carried forward to week 12
  4. c p < 0.01 for paired t-test comparing week 12 versus baseline
  5. d p < 0.05 for paired t-test comparing week 12 versus baseline
  6. e p < 0.001 for paired t-test comparing week 12 versus baseline